NOIDA (CoinChapter.com) — Bitcoin Exchange-Traded Funds (ETFs) are back in focus after a fresh surge in institutional inflows. On Apr. 21, 2025, US spot Bitcoin ETFs recorded a net inflow of $383 million—their highest single-day inflow since January—according to Bloomberg and Bitwise Europe.
The spike reflects growing institutional interest following a choppy first quarter, during which January saw steep outflows before the trend began reversing in March. Parallel to the US momentum, European Bitcoin Exchange-Traded Products (ETPs) also attracted €50 million in inflows, further supporting the narrative of global institutional re-engagement with the crypto asset class.
Bitcoin ETF Flows and Global Implications
The April 21 inflows, confirmed by Bitwise Europe’s André Dragosch, signal renewed investor confidence in Bitcoin ETFs as macro conditions stabilize. BlackRock’s iShares Bitcoin Trust (IBIT) and Fidelity’s Wise Origin Bitcoin Fund (FBTC) dominated the uptick, accounting for most inflows.

The day before, on April 20, US Bitcoin ETFs had already attracted $250 million, setting up the conditions for the following surge.
Importantly, outflows from Grayscale’s Bitcoin Trust (GBTC) have now slowed sharply. Only $10 million exited GBTC on Apr. 20, a stark contrast to the early 2025 trend when it led ETF outflows amid broader market retracements.

The shift suggests institutional investors are regaining trust in structured crypto products, especially those tied to major asset managers. Reports earlier this year highlighted how IBIT and FBTC have emerged as preferred ETF vehicles due to lower fees and greater liquidity.
The European side of the market appears to be mirroring these moves. A separate analyst noted that $53.5 million entered Bitcoin ETPs across major European exchanges on April 21, aligning with the broader uptrend in the US.
Analyst predictions on X project that Bitcoin’s institutional tailwind could push prices as high as $200,000 by year-end, others caution that macroeconomic headwinds remain. Potential interest rate hikes from the US Federal Reserve, particularly at the June FOMC meeting, could dampen appetite for risk assets.
Nonetheless, the ongoing surge in ETF flows signals a bullish institutional outlook, positioning Bitcoin as a growing fixture in traditional investment portfolios. This trend could further integrate Bitcoin into mainstream financial infrastructure through 2025 and beyond if sustained.
BTC Price Faces Key Test After Channel Breakout
Bitcoin (BTC) has broken out of an ascending parallel channel on the daily chart, confirming a bullish structural shift for the first time since mid-March. The breakout carried BTC price past the cluster of short-term EMAs and now sees it trading just above its 100-day EMA (blue), which is now acting as dynamic support.
The technical breakout coincides with renewed institutional interest, as US spot Bitcoin ETFs attracted their highest daily total inflows since Jan. 2025. The surge in ETF demand has added fuel to Bitcoin’s upside momentum, reinforcing the case for a broader trend reversal. Importantly, the inflows reflect a shift in investor appetite toward regulated Bitcoin exposure, especially via funds managed by BlackRock and Fidelity.

Despite these tailwinds, Bitcoin’s price action is now contending with a familiar hurdle near the $88,000–$89,000 zone. This region has previously triggered sharp rejections. Clearing this range could open the path toward a resistance level near $91,000. Flipping the immediate resistance would help Bitcoin price target the resistance near $95,000, anchored by a high-volume node at $94,980 and the 78.6% Fib retracement level.
Volume has increased post-breakout, though conviction remains moderate. RSI sits just below 60, suggesting more room for upward movement, though recent divergence signals the need for caution. On the downside, the 200-day EMA and the $85,600 mark form immediate support. A break below this region could expose BTC to $82,100 and eventually retest the lower bounds of the previously broken channel.
Though BTC price has found backing from ETF flows, bulls have their task cut out if Bitcoin needs to break past the next resistance levels.